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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN1
All Species:
4.55
Human Site:
T596
Identified Species:
7.69
UniProt:
Q16512
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16512
NP_002732.3
942
103932
T596
L
P
S
E
T
Q
E
T
P
G
P
A
L
C
S
Chimpanzee
Pan troglodytes
XP_512443
1169
127241
T823
L
P
S
E
T
R
E
T
P
G
P
A
P
V
Q
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
M648
P
R
T
K
R
P
H
M
E
P
R
T
R
R
G
Dog
Lupus familis
XP_542019
1076
118222
E729
E
P
P
S
E
T
Q
E
T
P
G
P
A
L
S
Cat
Felis silvestris
Mouse
Mus musculus
P70268
946
104392
E599
E
L
P
S
E
T
Q
E
T
P
G
P
G
L
C
Rat
Rattus norvegicus
Q63433
946
104449
E599
E
L
P
S
E
T
Q
E
T
P
G
P
G
L
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
G636
K
R
P
H
M
E
D
G
S
N
S
R
G
S
H
Chicken
Gallus gallus
XP_422357
1013
114806
M620
I
C
E
P
S
S
E
M
K
A
P
D
M
P
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689331
948
107057
H605
V
T
T
P
I
R
T
H
S
L
S
S
K
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
K322
G
K
V
M
L
A
E
K
K
G
T
D
E
I
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
A395
S
F
G
K
V
M
L
A
E
R
K
G
T
D
E
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
Q456
T
Q
G
Q
H
G
A
Q
E
I
S
A
M
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
S781
E
V
L
Q
E
T
V
S
L
A
P
T
S
T
H
Red Bread Mold
Neurospora crassa
P87253
1142
127954
Q754
Q
Q
Q
Q
Q
Q
Q
Q
T
P
Q
Q
V
S
P
Conservation
Percent
Protein Identity:
100
79.3
38.7
83
N.A.
91.6
91.9
N.A.
42.2
57.6
N.A.
66.7
N.A.
29
N.A.
27.8
48.5
Protein Similarity:
100
79.9
52.6
84.3
N.A.
94.7
94.6
N.A.
56.1
72.1
N.A.
79.5
N.A.
42.8
N.A.
43.4
61.7
P-Site Identity:
100
73.3
0
13.3
N.A.
0
0
N.A.
0
13.3
N.A.
0
N.A.
13.3
N.A.
0
6.6
P-Site Similarity:
100
80
13.3
20
N.A.
6.6
6.6
N.A.
13.3
40
N.A.
26.6
N.A.
13.3
N.A.
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.8
28.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.4
45.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
8
8
0
15
0
22
8
0
8
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
15
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
0
15
0
15
8
% D
% Glu:
29
0
8
15
29
8
29
22
22
0
0
0
8
0
8
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
15
0
0
8
0
8
0
22
22
8
22
0
8
% G
% His:
0
0
0
8
8
0
8
8
0
0
0
0
0
0
15
% H
% Ile:
8
0
0
0
8
0
0
0
0
8
0
0
0
8
0
% I
% Lys:
8
8
0
15
0
0
0
8
15
0
8
0
8
0
8
% K
% Leu:
15
15
8
0
8
0
8
0
8
8
0
0
8
22
0
% L
% Met:
0
0
0
8
8
8
0
15
0
0
0
0
15
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
8
22
29
15
0
8
0
0
15
36
29
22
8
8
8
% P
% Gln:
8
15
8
22
8
15
29
15
0
0
8
8
0
8
8
% Q
% Arg:
0
15
0
0
8
15
0
0
0
8
8
8
8
8
0
% R
% Ser:
8
0
15
22
8
8
0
8
15
0
22
8
8
15
15
% S
% Thr:
8
8
15
0
15
29
8
15
29
0
8
15
8
8
0
% T
% Val:
8
8
8
0
8
0
8
0
0
0
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _